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Vaccination with VLPs Presenting a Linear Neutralizing Domain of S. aureus Hla Elicits Protective Immunity
The pore-forming cytotoxin α-hemolysin, or Hla, is a critical Staphylococcus aureus virulence factor that promotes infection by causing tissue damage, excessive inflammation, and lysis of both innate and adaptive immune cells, among other cellular targets. In this study, we asked whether a virus-lik...
Autores principales: | Joyner, Jason A., Daly, Seth M., Peabody, Julianne, Triplett, Kathleen D., Pokhrel, Srijana, Elmore, Bradley O., Adebanjo, Diane, Peabody, David S., Chackerian, Bryce, Hall, Pamela R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404987/ https://www.ncbi.nlm.nih.gov/pubmed/32664481 http://dx.doi.org/10.3390/toxins12070450 |
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