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Clostridium difficile toxins or infection induce upregulation of adenosine receptors and IL-6 with early pro-inflammatory and late anti-inflammatory pattern

Clostridium difficile causes intestinal inflammation, which increases adenosine. We compared the expression of adenosine receptors (AR) subtypes A(1)(, A)(2A)(, A)(2B)(, and A)(3) in HCT-8, IEC-6 cells, and isolated intestinal epithelial cells, challenged or not with Clostridium difficile toxin A an...

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Detalles Bibliográficos
Autores principales: Foschetti, D.A., Braga-Neto, M.B., Bolick, D., Moore, J., Alves, LA., Martins, CS., Bomfin, LE., Santos, AAQA., Leitão, RFC., Brito, GAC., Warren, CA.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405017/
https://www.ncbi.nlm.nih.gov/pubmed/32725081
http://dx.doi.org/10.1590/1414-431X20209877