MASP2 levels are elevated in thrombotic microangiopathies: association with microvascular endothelial cell injury and suppression by anti‐MASP2 antibody narsoplimab

Involvement of the alternative complement pathway (AP) in microvascular endothelial cell (MVEC) injury characteristic of a thrombotic microangiopathy (TMA) is well documented. However, the role of the lectin pathway (LP) of complement has not been explored. We examined mannose‐binding lectin associa...

Descripción completa

Detalles Bibliográficos
Autores principales: Elhadad, S., Chapin, J., Copertino, D., Van Besien, K., Ahamed, J., Laurence, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405159/
https://www.ncbi.nlm.nih.gov/pubmed/32681658
http://dx.doi.org/10.1111/cei.13497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405159/
https://www.ncbi.nlm.nih.gov/pubmed/32681658
http://dx.doi.org/10.1111/cei.13497

Ejemplares similares