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Large CRISPR-Cas-induced deletions in the oxamniquine resistance locus of the human parasite Schistosoma mansoni

Background. At least 250 million people worldwide suffer from schistosomiasis, caused by Schistosoma worms. Genome sequences for several Schistosoma species are available, including a high-quality annotated reference for Schistosoma mansoni. There is a pressing need to develop a reliable functional...

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Detalles Bibliográficos
Autores principales: Sankaranarayanan, Geetha, Coghlan, Avril, Driguez, Patrick, Lotkowska, Magda E., Sanders, Mandy, Holroyd, Nancy, Tracey, Alan, Berriman, Matthew, Rinaldi, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405262/
https://www.ncbi.nlm.nih.gov/pubmed/32789192
http://dx.doi.org/10.12688/wellcomeopenres.16031.2