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Large CRISPR-Cas-induced deletions in the oxamniquine resistance locus of the human parasite Schistosoma mansoni
Background. At least 250 million people worldwide suffer from schistosomiasis, caused by Schistosoma worms. Genome sequences for several Schistosoma species are available, including a high-quality annotated reference for Schistosoma mansoni. There is a pressing need to develop a reliable functional...
Autores principales: | Sankaranarayanan, Geetha, Coghlan, Avril, Driguez, Patrick, Lotkowska, Magda E., Sanders, Mandy, Holroyd, Nancy, Tracey, Alan, Berriman, Matthew, Rinaldi, Gabriel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405262/ https://www.ncbi.nlm.nih.gov/pubmed/32789192 http://dx.doi.org/10.12688/wellcomeopenres.16031.2 |
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