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Functions of mammalian SIRT4 in cellular metabolism and research progress in human cancer

Sirtuins are mammalian homologs of yeast silent information regulator two (SIRT) and are a highly conserved family of proteins, which act as nicotinamide adenine dinucleotide (NAD(+))-dependent histone deacetylases. The seven sirtuins (SIRT1-7) share a conserved catalytic core domain; however, they...

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Detalles Bibliográficos
Autores principales: Wang, Changming, Liu, Yan, Zhu, Yuyan, Kong, Chuize
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405384/
https://www.ncbi.nlm.nih.gov/pubmed/32774484
http://dx.doi.org/10.3892/ol.2020.11872