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UGT1A1 polymorphism has a prognostic effect in patients with stage IB or II uterine cervical cancer and one or no metastatic pelvic nodes receiving irinotecan chemotherapy: a retrospective study

BACKGROUND: Uridine diphosphate glucuronosyltransferase 1 family polypeptide A1 (UGT1A1) is a predictive biomarker for the side-effects of irinotecan chemotherapy, which reduces the volume of tumors harboring UGT1A1 polymorphisms. We aimed to determine whether UGT1A1 polymorphisms can predict progre...

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Detalles Bibliográficos
Autores principales: Matsuoka, Hideki, Murakami, Ryusuke, Abiko, Kaoru, Yamaguchi, Ken, Horie, Akihito, Hamanishi, Junzo, Baba, Tsukasa, Mandai, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405427/
https://www.ncbi.nlm.nih.gov/pubmed/32758288
http://dx.doi.org/10.1186/s12885-020-07225-1