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Retinoschisin and Cardiac Glycoside Crosstalk at the Retinal Na/K-ATPase

PURPOSE: Mutations in the RS1 gene, which encodes retinoschisin, cause X-linked juvenile retinoschisis, a retinal dystrophy in males. Retinoschisin specifically interacts with the retinal sodium–potassium adenosine triphosphatase (Na/K-ATPase), a transmembrane ion pump. Na/K-ATPases also bind cardia...

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Detalles Bibliográficos
Autores principales: Schmid, Verena, Plössl, Karolina, Schmid, Carina, Bernklau, Sarah, Weber, Bernhard H. F., Friedrich, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405613/
https://www.ncbi.nlm.nih.gov/pubmed/32392309
http://dx.doi.org/10.1167/iovs.61.5.1