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Functional Evaluation of AMD-Associated Risk Variants of Complement Factor B
PURPOSE: The 32W and 32Q variants of complement factor B (CFB) are associated with reduced risk of developing neovascular age-related macular degeneration (AMD) compared with the common 32R allele. The objective of this study was to determine if the most protective R32Q variant affects the neovascul...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405614/ https://www.ncbi.nlm.nih.gov/pubmed/32407521 http://dx.doi.org/10.1167/iovs.61.5.19 |