Cargando…
Functional Evaluation of AMD-Associated Risk Variants of Complement Factor B
PURPOSE: The 32W and 32Q variants of complement factor B (CFB) are associated with reduced risk of developing neovascular age-related macular degeneration (AMD) compared with the common 32R allele. The objective of this study was to determine if the most protective R32Q variant affects the neovascul...
Autores principales: | Pilotti, Camilla, Greenwood, John, Moss, Stephen E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405614/ https://www.ncbi.nlm.nih.gov/pubmed/32407521 http://dx.doi.org/10.1167/iovs.61.5.19 |
Ejemplares similares
-
A Targeted Inhibitor of the Alternative Complement Pathway Accelerates Recovery From Smoke-Induced Ocular Injury
por: Woodell, Alex, et al.
Publicado: (2016) -
Complement-Mediated Regulation of Apolipoprotein E in Cultured Human RPE Cells
por: Yang, Ping, et al.
Publicado: (2017) -
Manifestations of intraocular inflammation over time in patients on brolucizumab for neovascular AMD
por: Khoramnia, Ramin, et al.
Publicado: (2021) -
Effect of aflibercept in insufficient responders to prior anti-VEGF therapy in neovascular AMD
por: Fassnacht-Riederle, Heidi, et al.
Publicado: (2014) -
Impact of intravitreal injection therapy on contrast sensitivity in patients with nAMD and DME
por: Dieke, Sebastian, et al.
Publicado: (2023)