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Somatic mutations in genes associated with mismatch repair predict survival in patients with metastatic cancer receiving immune checkpoint inhibitors

Immune checkpoint inhibitors (ICIs) have emerged as one of the most promising therapeutic options for patients with advanced cancer. The aim of the present study was to investigate the prognostic value of somatic mutations in mismatch repair (MMR) genes in metastatic cancers after ICI treatment, as...

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Detalles Bibliográficos
Autores principales: Liu, Yongping, Chen, Lin, Zhang, Shenli, Shu, Yimei, Qi, Qiufeng, Zhu, Ming, Peng, Yun, Ling, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405634/
https://www.ncbi.nlm.nih.gov/pubmed/32774500
http://dx.doi.org/10.3892/ol.2020.11888