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Agrin Promotes Limbal Stem Cell Proliferation and Corneal Wound Healing Through Hippo-Yap Signaling Pathway

PURPOSE: To investigate the effect and mechanism of Agrin on limbal stem cell proliferation and corneal wound healing. METHODS: Limbal stem cells were isolated and treated with different concentrations of Agrin. CCK-8 and cell proliferation markers (Ki67 and pH3) were detected to evaluate cell numbe...

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Detalles Bibliográficos
Autores principales: Hou, Lulu, Fu, Wenbin, Liu, Ying, Wang, Qun, Wang, Liqiang, Huang, Yifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405682/
https://www.ncbi.nlm.nih.gov/pubmed/32392315
http://dx.doi.org/10.1167/iovs.61.5.7