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ISG15 Acts as a Mediator of Innate Immune Response to Pseudomonas aeruginosa Infection in C57BL/6J Mouse Corneas

PURPOSE: IFN-stimulated gene (ISG) 15 is a type 1 IFN-induced protein and known to modify target proteins in a manner similar to ubiquitylation (protein conjugation by ISG15 is termed ISGylation). We sought to determine the role of ISG15 and its underlying mechanisms in corneal innate immune defense...

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Detalles Bibliográficos
Autores principales: Gao, Nan, Me, Rao, Dai, Chenyang, Yu, Fu-shin X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405721/
https://www.ncbi.nlm.nih.gov/pubmed/32416603
http://dx.doi.org/10.1167/iovs.61.5.26