Structural analysis of ACE2 variant N720D demonstrates a higher binding affinity to TMPRSS2

AIMS: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel member of the betacoronaviruses family affecting the lower respiratory tract mainly through binding to angiotensin converting enzyme 2 (ACE2) via its S-protein. Genetic analysis of (ACE2) gene revealed several variants that...

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Detalles Bibliográficos
Autores principales: Mohammad, Anwar, Marafie, Sulaiman K., Alshawaf, Eman, Abu-Farha, Mohamed, Abubaker, Jehad, Al-Mulla, Fahd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405906/
https://www.ncbi.nlm.nih.gov/pubmed/32768580
http://dx.doi.org/10.1016/j.lfs.2020.118219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405906/
https://www.ncbi.nlm.nih.gov/pubmed/32768580
http://dx.doi.org/10.1016/j.lfs.2020.118219

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