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Structural analysis of ACE2 variant N720D demonstrates a higher binding affinity to TMPRSS2
AIMS: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel member of the betacoronaviruses family affecting the lower respiratory tract mainly through binding to angiotensin converting enzyme 2 (ACE2) via its S-protein. Genetic analysis of (ACE2) gene revealed several variants that...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Authors. Published by Elsevier Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405906/ https://www.ncbi.nlm.nih.gov/pubmed/32768580 http://dx.doi.org/10.1016/j.lfs.2020.118219 |