Assay validation and determination of in vitro binding of mefloquine to plasma proteins from clinically normal and FIP-affected cats

The antimalarial agent mefloquine is currently being investigated for its potential to inhibit feline coronavirus and feline calicivirus infections. A simple, high pressure liquid chromatography assay was developed to detect mefloquine plasma concentrations in feline plasma. The assay’s lower limit...

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Detalles Bibliográficos
Autores principales: Izes, Aaron M., Kimble, Benjamin, Norris, Jacqueline M., Govendir, Merran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406051/
https://www.ncbi.nlm.nih.gov/pubmed/32756590
http://dx.doi.org/10.1371/journal.pone.0236754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406051/
https://www.ncbi.nlm.nih.gov/pubmed/32756590
http://dx.doi.org/10.1371/journal.pone.0236754

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