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Assay validation and determination of in vitro binding of mefloquine to plasma proteins from clinically normal and FIP-affected cats
The antimalarial agent mefloquine is currently being investigated for its potential to inhibit feline coronavirus and feline calicivirus infections. A simple, high pressure liquid chromatography assay was developed to detect mefloquine plasma concentrations in feline plasma. The assay’s lower limit...
Autores principales: | Izes, Aaron M., Kimble, Benjamin, Norris, Jacqueline M., Govendir, Merran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406051/ https://www.ncbi.nlm.nih.gov/pubmed/32756590 http://dx.doi.org/10.1371/journal.pone.0236754 |
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