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Comparative transcriptome analysis of endemic and epidemic Kaposi’s sarcoma (KS) lesions and the secondary role of HIV-1 in KS pathogenesis

In sub-Saharan Africa, endemic Kaposi’s sarcoma (EnKS) is still prevalent despite high incidence of epidemic Kaposi’s sarcoma (EpKS) resulting from the on-going HIV-1 epidemic. While KSHV is clearly the etiologic agent of KS, the mechanisms underlying KS development are not fully understood. For exa...

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Detalles Bibliográficos
Autores principales: Lidenge, Salum J., Kossenkov, Andrew V., Tso, For Yue, Wickramasinghe, Jayamanna, Privatt, Sara R., Ngalamika, Owen, Ngowi, John R., Mwaiselage, Julius, Lieberman, Paul M., West, John T., Wood, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406108/
https://www.ncbi.nlm.nih.gov/pubmed/32706839
http://dx.doi.org/10.1371/journal.ppat.1008681