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Distinct Bacterial Pathways Influence the Efficacy of Antibiotics against Mycobacterium tuberculosis

Effective tuberculosis treatment requires at least 6 months of combination therapy. Alterations in the physiological state of the bacterium during infection are thought to reduce drug efficacy and prolong the necessary treatment period, but the nature of these adaptations remain incompletely defined...

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Detalles Bibliográficos
Autores principales: Bellerose, Michelle M., Proulx, Megan K., Smith, Clare M., Baker, Richard E., Ioerger, Thomas R., Sassetti, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406225/
https://www.ncbi.nlm.nih.gov/pubmed/32753506
http://dx.doi.org/10.1128/mSystems.00396-20