Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms

The Arp2/3 complex regulates many cellular processes by stimulating formation of branched actin filament networks. Because three of its seven subunits exist as two different isoforms, mammals produce a family of Arp2/3 complexes with different properties that may be suited to different physiological...

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Detalles Bibliográficos
Autores principales: von Loeffelholz, Ottilie, Purkiss, Andrew, Cao, Luyan, Kjaer, Svend, Kogata, Naoko, Romet-Lemonne, Guillaume, Way, Michael, Moores, Carolyn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406314/
https://www.ncbi.nlm.nih.gov/pubmed/32661131
http://dx.doi.org/10.1242/bio.054304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406314/
https://www.ncbi.nlm.nih.gov/pubmed/32661131
http://dx.doi.org/10.1242/bio.054304

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