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A lineage-tracing tool to map the fate of hypoxic tumour cells

Intratumoural hypoxia is a common characteristic of malignant treatment-resistant cancers. However, hypoxia-modification strategies for the clinic remain elusive. To date, little is known on the behaviour of individual hypoxic tumour cells in their microenvironment. To explore this issue in a spatia...

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Detalles Bibliográficos
Autores principales: Vermeer, Jenny A. F., Ient, Jonathan, Markelc, Bostjan, Kaeppler, Jakob, Barbeau, Lydie M. O., Groot, Arjan J., Muschel, Ruth J., Vooijs, Marc A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406318/
https://www.ncbi.nlm.nih.gov/pubmed/32571767
http://dx.doi.org/10.1242/dmm.044768