Early evidence of delayed oligodendrocyte maturation in the mouse model of mucolipidosis type IV

Mucolipidosis type IV (MLIV) is a lysosomal disease caused by mutations in the MCOLN1 gene that encodes the endolysosomal transient receptor potential channel mucolipin-1, or TRPML1. MLIV results in developmental delay, motor and cognitive impairments, and vision loss. Brain abnormalities include th...

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Detalles Bibliográficos
Autores principales: Mepyans, Molly, Andrzejczuk, Livia, Sosa, Jahree, Smith, Sierra, Herron, Shawn, DeRosa, Samantha, Slaugenhaupt, Susan A., Misko, Albert, Grishchuk, Yulia, Kiselyov, Kirill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406328/
https://www.ncbi.nlm.nih.gov/pubmed/32586947
http://dx.doi.org/10.1242/dmm.044230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406328/
https://www.ncbi.nlm.nih.gov/pubmed/32586947
http://dx.doi.org/10.1242/dmm.044230

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