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Membrane voltage dysregulation driven by metabolic dysfunction underlies bactericidal activity of aminoglycosides
Aminoglycosides are broad-spectrum antibiotics whose mechanism of action is under debate. It is widely accepted that membrane voltage potentiates aminoglycoside activity, which is ascribed to voltage-dependent drug uptake. In this paper, we measured the response of Escherichia coli treated with amin...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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eLife Sciences Publications, Ltd
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406350/ https://www.ncbi.nlm.nih.gov/pubmed/32748785 http://dx.doi.org/10.7554/eLife.58706 |