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Cdc13 is predominant over Stn1 and Ten1 in preventing chromosome end fusions

Telomeres define the natural ends of eukaryotic chromosomes and are crucial for chromosomal stability. The budding yeast Cdc13, Stn1 and Ten1 proteins form a heterotrimeric complex, and the inactivation of any of its subunits leads to a uniformly lethal phenotype due to telomere deprotection. Althou...

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Detalles Bibliográficos
Autores principales: Wu, Zhi-Jing, Liu, Jia-Cheng, Man, Xin, Gu, Xin, Li, Ting-Yi, Cai, Chen, He, Ming-Hong, Shao, Yangyang, Lu, Ning, Xue, Xiaoli, Qin, Zhongjun, Zhou, Jin-Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406354/
https://www.ncbi.nlm.nih.gov/pubmed/32755541
http://dx.doi.org/10.7554/eLife.53144