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Molecular recognition of human islet amyloid polypeptide assembly by selective oligomerization of thioflavin T

Selective oligomerization is a common phenomenon existing widely in the formation of intricate biological structures in nature. The precise design of drug molecules with an oligomerization state that specifically recognizes its receptor, however, remains substantially challenging. Here, we used scan...

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Detalles Bibliográficos
Autores principales: Yu, Lanlan, Zhang, Wenbo, Luo, Wendi, Dupont, Robert L., Xu, Yang, Wang, Yibing, Tu, Bin, Xu, Haiyan, Wang, Xiaoguang, Fang, Qiaojun, Yang, Yanlian, Wang, Chen, Wang, Chenxuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406363/
https://www.ncbi.nlm.nih.gov/pubmed/32821844
http://dx.doi.org/10.1126/sciadv.abc1449