Cargando…

Recent advances in siRNA delivery mediated by lipid-based nanoparticles

Small interfering RNA (siRNA) has been expected to be a unique pharmaceutic for the treatment of broad-spectrum intractable diseases. However, its unfavorable properties such as easy degradation in the blood and negative-charge density are still a formidable barrier for clinical use. For disruption...

Descripción completa

Detalles Bibliográficos
Autores principales: Yonezawa, Sei, Koide, Hiroyuki, Asai, Tomohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406478/
https://www.ncbi.nlm.nih.gov/pubmed/32768564
http://dx.doi.org/10.1016/j.addr.2020.07.022