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Recent advances in siRNA delivery mediated by lipid-based nanoparticles
Small interfering RNA (siRNA) has been expected to be a unique pharmaceutic for the treatment of broad-spectrum intractable diseases. However, its unfavorable properties such as easy degradation in the blood and negative-charge density are still a formidable barrier for clinical use. For disruption...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406478/ https://www.ncbi.nlm.nih.gov/pubmed/32768564 http://dx.doi.org/10.1016/j.addr.2020.07.022 |