BECN1 promotes radiation-induced G2/M arrest through regulation CDK1 activity: a potential role for autophagy in G2/M checkpoint

Authophagy and G2/M arrest are two important mechanistic responses of cells to ionizing radiation (IR), in particular the IR-induced fibrosis. However, what interplayer and how it links the autophagy and the G(2)/M arrest remains elusive. Here, we demonstrate that the autophagy-related protein BECN1...

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Detalles Bibliográficos
Autores principales: Huang, Ruixue, Gao, Shanshan, Han, Yanqin, Ning, Huacheng, Zhou, Yao, Guan, Hua, Liu, Xiaodan, Yan, Shuang, Zhou, Ping-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406511/
https://www.ncbi.nlm.nih.gov/pubmed/32802407
http://dx.doi.org/10.1038/s41420-020-00301-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406511/
https://www.ncbi.nlm.nih.gov/pubmed/32802407
http://dx.doi.org/10.1038/s41420-020-00301-2

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