Vectorial transport of the arginine derivatives asymmetric dimethylarginine (ADMA) and l-homoarginine by OATP4C1 and P-glycoprotein studied in double-transfected MDCK cells

Elevated plasma concentrations of the uremic toxin asymmetric dimethylarginine (ADMA) and low plasma concentrations of l-homoarginine are independently associated with cardiovascular events and mortality. Key enzymes involved in the homeostasis of both arginine derivatives are expressed in proximal...

Descripción completa

Detalles Bibliográficos
Autores principales: Taghikhani, Emir, Maas, Renke, Taudte, R. Verena, Gessner, Arne, Fromm, Martin F., König, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406541/
https://www.ncbi.nlm.nih.gov/pubmed/32642843
http://dx.doi.org/10.1007/s00726-020-02867-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406541/
https://www.ncbi.nlm.nih.gov/pubmed/32642843
http://dx.doi.org/10.1007/s00726-020-02867-8

Ejemplares similares