Degradation of SAMHD1 Restriction Factor Through Cullin-Ring E3 Ligase Complexes During Human Cytomegalovirus Infection

Sterile alpha motif (SAM) and histidine-aspartate (HD) domain-containing protein 1 (SAMHD1) acts as a restriction factor for several RNA and DNA viruses by limiting the intracellular pool of deoxynucleoside triphosphates. Here, we investigated the regulation of SAMHD1 expression during human cytomeg...

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Detalles Bibliográficos
Autores principales: Hyeon, Seokhwan, Lee, Myoung Kyu, Kim, Young-Eui, Lee, Gwang Myeong, Ahn, Jin-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406573/
https://www.ncbi.nlm.nih.gov/pubmed/32850489
http://dx.doi.org/10.3389/fcimb.2020.00391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406573/
https://www.ncbi.nlm.nih.gov/pubmed/32850489
http://dx.doi.org/10.3389/fcimb.2020.00391

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