RINT1 Loss Impairs Retinogenesis Through TRP53-Mediated Apoptosis

Genomic instability in the central nervous system (CNS) is associated with defective neurodevelopment and neurodegeneration. Congenital human syndromes that affect the CNS development originate from mutations in genes of the DNA damage response (DDR) pathways. RINT1 (Rad50-interacting protein 1) is...

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Detalles Bibliográficos
Autores principales: Gomes, Anielle L., Matos-Rodrigues, Gabriel E., Frappart, Pierre-Olivier, Martins, Rodrigo A. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406574/
https://www.ncbi.nlm.nih.gov/pubmed/32850831
http://dx.doi.org/10.3389/fcell.2020.00711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406574/
https://www.ncbi.nlm.nih.gov/pubmed/32850831
http://dx.doi.org/10.3389/fcell.2020.00711

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