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In vivo and in silico characterization of apocynin in reducing organ oxidative stress: A pharmacokinetic and pharmacodynamic study
Apocynin has been widely used in vivo as a Nox2‐contaninig nicotinamide adenine dinucleotide phosphate oxidase inhibitor. However, its time‐dependent tissue distribution and inhibition on organ reactive oxygen species (ROS) production remained unclear. In this study, we examined apocynin pharmacokin...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406636/ https://www.ncbi.nlm.nih.gov/pubmed/32761799 http://dx.doi.org/10.1002/prp2.635 |