AUF1 promotes stemness in human mammary epithelial cells through stabilization of the EMT transcription factors TWIST1 and SNAIL1

The AU-rich element RNA-binding protein 1 (AUF1) is an RNA-binding protein, which can both stabilize and destabilize the transcripts of several cancer-related genes. Since epithelial-to-mesenchymal transition (EMT) and the acquisition of cancer stem cell traits are important for cancer onset and pro...

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Detalles Bibliográficos
Autores principales: AlAhmari, Manar M., Al-Khalaf, Huda H., Al-Mohanna, Falah H., Ghebeh, Hazem, Aboussekhra, Abdelilah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406652/
https://www.ncbi.nlm.nih.gov/pubmed/32759946
http://dx.doi.org/10.1038/s41389-020-00255-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406652/
https://www.ncbi.nlm.nih.gov/pubmed/32759946
http://dx.doi.org/10.1038/s41389-020-00255-1

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