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AUF1 promotes stemness in human mammary epithelial cells through stabilization of the EMT transcription factors TWIST1 and SNAIL1
The AU-rich element RNA-binding protein 1 (AUF1) is an RNA-binding protein, which can both stabilize and destabilize the transcripts of several cancer-related genes. Since epithelial-to-mesenchymal transition (EMT) and the acquisition of cancer stem cell traits are important for cancer onset and pro...
Autores principales: | AlAhmari, Manar M., Al-Khalaf, Huda H., Al-Mohanna, Falah H., Ghebeh, Hazem, Aboussekhra, Abdelilah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406652/ https://www.ncbi.nlm.nih.gov/pubmed/32759946 http://dx.doi.org/10.1038/s41389-020-00255-1 |
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