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Heterotypic immunity against vaccinia virus in an HLA-B*07:02 transgenic mousepox infection model

Vaccination with vaccinia virus (VACV) elicits heterotypic immunity to smallpox, monkeypox, and mousepox, the mechanistic basis for which is poorly understood. It is generally assumed that heterotypic immunity arises from the presentation of a wide array of VACV-derived, CD8(+) T cell epitopes that...

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Detalles Bibliográficos
Autores principales: Kumar, Amrendra, Suryadevara, Naveen Chandra, Wolf, Kyle J., Wilson, John T., Di Paolo, Richard J., Brien, James D., Joyce, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406653/
https://www.ncbi.nlm.nih.gov/pubmed/32759969
http://dx.doi.org/10.1038/s41598-020-69897-w