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Considerations of Antibody Geometric Constraints on NK Cell Antibody Dependent Cellular Cytotoxicity
It has been well-established that antibody isotype, glycosylation, and epitope all play roles in the process of antibody dependent cellular cytotoxicity (ADCC). For natural killer (NK) cells, these phenotypes are linked to cellular activation through interaction with the IgG receptor FcγRIIIa, a sin...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406664/ https://www.ncbi.nlm.nih.gov/pubmed/32849559 http://dx.doi.org/10.3389/fimmu.2020.01635 |