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N,N’ bis-(2-mercaptoethyl) isophthalamide induces developmental delay in Caenorhabditis elegans by promoting DAF-16 nuclear localization

N,N’ bis-(2-mercaptoethyl) isophthalamide (NBMI) is a lipophilic thiol-containing agent that has high affinity for toxic metal ions, such as Hg(2+), Pb(2+), and Cd(2+). Studies have shown that NBMI is a potent chelator of heavy metals, yet its potential toxicity in animals has yet to be determined....

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Detalles Bibliográficos
Autores principales: Ke, Tao, Antunes Soares, Félix Alexandre, Santamaría, Abel, Bowman, Aaron B., Skalny, Anatoly V., Aschner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406974/
https://www.ncbi.nlm.nih.gov/pubmed/32793422
http://dx.doi.org/10.1016/j.toxrep.2020.07.012