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An in vitromodel to quantify interspecies differences in kinetics for intestinal microbial bioactivation and detoxification of zearalenone

Zearalenone (ZEN) is a mycotoxin known for its estrogenic activities. The metabolism of ZEN plays a role in the interspecies differences in sensitivity to ZEN, and is known to occur in the liver and via the intestinal microbiota, although the relative contribution of these two pathways remains to be...

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Detalles Bibliográficos
Autores principales: Mendez-Catala, Diana M., Spenkelink, Albertus, Rietjens, Ivonne M.C.M., Beekmann, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406981/
https://www.ncbi.nlm.nih.gov/pubmed/32793423
http://dx.doi.org/10.1016/j.toxrep.2020.07.010