Human Cytomegalovirus miR-US5-2 Downregulation of GAB1 Regulates Cellular Proliferation and UL138 Expression through Modulation of Epidermal Growth Factor Receptor Signaling Pathways

Regulation of epidermal growth factor (EGF) receptor (EGFR) signaling is critical for the replication of human cytomegalovirus (HCMV) as well as latency and reactivation in CD34(+) hematopoietic progenitor cells. HCMV microRNAs (miRNAs) provide a means to modulate the signaling activated by EGF thro...

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Detalles Bibliográficos
Autores principales: Hancock, Meaghan H., Mitchell, Jennifer, Goodrum, Felicia D., Nelson, Jay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407068/
https://www.ncbi.nlm.nih.gov/pubmed/32759334
http://dx.doi.org/10.1128/mSphere.00582-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407068/
https://www.ncbi.nlm.nih.gov/pubmed/32759334
http://dx.doi.org/10.1128/mSphere.00582-20

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