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Application of the Reverse Fragility Index to Statistically Nonsignificant Randomized Clinical Trial Results

IMPORTANCE: Interpreting randomized clinical trials (RCTs) and their clinical relevance is challenging when P values are either marginally above or below the P = .05 threshold. OBJECTIVE: To use the concept of reverse fragility index (RFI) to provide a measure of confidence in the neutrality of RCT...

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Detalles Bibliográficos
Autores principales: Khan, Muhammad Shahzeb, Fonarow, Gregg C., Friede, Tim, Lateef, Noman, Khan, Safi U., Anker, Stefan D., Harrell, Frank E., Butler, Javed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407075/
https://www.ncbi.nlm.nih.gov/pubmed/32756927
http://dx.doi.org/10.1001/jamanetworkopen.2020.12469