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Methylglyoxal Detoxification Revisited: Role of Glutathione Transferase in Model Cyanobacterium Synechocystis sp. Strain PCC 6803

Methylglyoxal (MG) is a detrimental metabolic by-product that threatens most organisms (in humans MG causes diabetes). MG is predominantly detoxified by the glyoxalase pathway. This process begins with the conjugation of MG with glutathione (GSH), yielding a hemithioacetal product that is subsequent...

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Detalles Bibliográficos
Autores principales: Kammerscheit, Xavier, Hecker, Arnaud, Rouhier, Nicolas, Chauvat, Franck, Cassier-Chauvat, Corinne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407080/
https://www.ncbi.nlm.nih.gov/pubmed/32753490
http://dx.doi.org/10.1128/mBio.00882-20