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PPP6C Negatively Regulates STING-Dependent Innate Immune Responses

Stimulator of interferon genes (STING) is an essential adaptor protein of the innate DNA-sensing signaling pathway, which recognizes genomic DNA from invading pathogens to establish antiviral responses in host cells. STING activity is tightly regulated by several posttranslational modifications, inc...

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Detalles Bibliográficos
Autores principales: Ni, Guoxin, Ma, Zhe, Wong, Jason P., Zhang, Zhigang, Cousins, Emily, Major, M. Ben, Damania, Blossom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407089/
https://www.ncbi.nlm.nih.gov/pubmed/32753499
http://dx.doi.org/10.1128/mBio.01728-20