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PPP6C Negatively Regulates STING-Dependent Innate Immune Responses
Stimulator of interferon genes (STING) is an essential adaptor protein of the innate DNA-sensing signaling pathway, which recognizes genomic DNA from invading pathogens to establish antiviral responses in host cells. STING activity is tightly regulated by several posttranslational modifications, inc...
Autores principales: | Ni, Guoxin, Ma, Zhe, Wong, Jason P., Zhang, Zhigang, Cousins, Emily, Major, M. Ben, Damania, Blossom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407089/ https://www.ncbi.nlm.nih.gov/pubmed/32753499 http://dx.doi.org/10.1128/mBio.01728-20 |
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