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The Pentose Phosphate Pathway Dynamics in Cancer and Its Dependency on Intracellular pH

The Pentose Phosphate Pathway (PPP) is one of the key metabolic pathways occurring in living cells to produce energy and maintain cellular homeostasis. Cancer cells have higher cytoplasmic utilization of glucose (glycolysis), even in the presence of oxygen; this is known as the “Warburg Effect”. How...

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Detalles Bibliográficos
Autores principales: Alfarouk, Khalid O., Ahmed, Samrein B. M., Elliott, Robert L., Benoit, Amanda, Alqahtani, Saad S., Ibrahim, Muntaser E., Bashir, Adil H. H., Alhoufie, Sari T. S., Elhassan, Gamal O., Wales, Christian C., Schwartz, Laurent H., Ali, Heyam S., Ahmed, Ahmed, Forde, Patrick F., Devesa, Jesus, Cardone, Rosa A., Fais, Stefano, Harguindey, Salvador, Reshkin, Stephan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407102/
https://www.ncbi.nlm.nih.gov/pubmed/32664469
http://dx.doi.org/10.3390/metabo10070285