Inhibition of HDAC1/2 Along with TRAP1 Causes Synthetic Lethality in Glioblastoma Model Systems

The heterogeneity of glioblastomas, the most common primary malignant brain tumor, remains a significant challenge for the treatment of these devastating tumors. Therefore, novel combination treatments are warranted. Here, we showed that the combined inhibition of TRAP1 by gamitrinib and histone dea...

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Detalles Bibliográficos
Autores principales: Nguyen, Trang T. T., Zhang, Yiru, Shang, Enyuan, Shu, Chang, Quinzii, Catarina M., Westhoff, Mike-Andrew, Karpel-Massler, Georg, Siegelin, Markus D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407106/
https://www.ncbi.nlm.nih.gov/pubmed/32664214
http://dx.doi.org/10.3390/cells9071661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407106/
https://www.ncbi.nlm.nih.gov/pubmed/32664214
http://dx.doi.org/10.3390/cells9071661

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