RORα Regulates Cholesterol Metabolism of CD8(+) T Cells for Anticancer Immunity

Retinoic acid-related orphan receptor α (RORα) functions as a transcription factor for various biological processes, including circadian rhythm, inflammation, cancer, and lipid metabolism. Here, we demonstrate that RORα is crucial for maintaining cholesterol homeostasis in CD8(+) T cells by attenuat...

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Detalles Bibliográficos
Autores principales: Lee, In Kyu, Song, Hyerin, Kim, Hyerim, Kim, Ik Soo, Tran, Na Ly, Kim, Sang-Heon, Oh, Seung Ja, Lee, Ji Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407186/
https://www.ncbi.nlm.nih.gov/pubmed/32610705
http://dx.doi.org/10.3390/cancers12071733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407186/
https://www.ncbi.nlm.nih.gov/pubmed/32610705
http://dx.doi.org/10.3390/cancers12071733

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