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Molecular Insights of Copper Sulfate Exposure-Induced Nephrotoxicity: Involvement of Oxidative and Endoplasmic Reticulum Stress Pathways

The precise pathogenic mechanism in Cu exposure-cause nephrotoxicity remains unclear. This study investigated the underlying molecular mechanism of copper sulfate (CuSO(4))-induced nephrotoxicity. Mice were treated with CuSO(4) at 50, 100, 200 mg/kg/day or co-treated with CuSO(4) (200 mg/kg/day) and...

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Detalles Bibliográficos
Autores principales: Dai, Chongshan, Liu, Qiangqiang, Li, Daowen, Sharma, Gaurav, Xiong, Jianli, Xiao, Xilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407214/
https://www.ncbi.nlm.nih.gov/pubmed/32650488
http://dx.doi.org/10.3390/biom10071010