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Chitosan-Based Microparticles Enhance Ellagic Acid’s Colon Targeting and Proapoptotic Activity

This study aimed at improving the targeting and cytotoxic effect of ellagic acid (EA) on colon cancer cells. EA was encapsulated in chitosan (CHIT) polymers then coated by eudragit S100 (ES100) microparticles. The release of EA double-coated microparticles (MPs) was tested at simulative pH values. M...

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Detalles Bibliográficos
Autores principales: Alhakamy, Nabil A., Ahmed, Osama A. A., Kurakula, Mallesh, Caruso, Giuseppe, Caraci, Filippo, Asfour, Hani Z., Alfarsi, Anas, Eid, Basma G., Mohamed, Amir I., K. Alruwaili, Nabil, Abdulaal, Wesam H., Fahmy, Usama A., Alhadrami, Hani A., Eldakhakhny, Basmah M., Abdel-Naim, Ashraf B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407221/
https://www.ncbi.nlm.nih.gov/pubmed/32660035
http://dx.doi.org/10.3390/pharmaceutics12070652