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A Survey of Reported Disease-Related Mutations in the MRE11-RAD50-NBS1 Complex
The MRE11-RAD50-NBS1 (MRN) protein complex is one of the primary vehicles for repairing DNA double strand breaks and maintaining the genomic stability within the cell. The role of the MRN complex to recognize and process DNA double-strand breaks as well as signal other damage response factors is cri...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407228/ https://www.ncbi.nlm.nih.gov/pubmed/32668560 http://dx.doi.org/10.3390/cells9071678 |