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Human Plasma-Derived 3D Cultures Model Breast Cancer Treatment Responses and Predict Clinically Effective Drug Treatment Concentrations

Lack of efficacy and a low overall success rate of phase I-II clinical trials are the most common failures when it comes to advancing cancer treatment. Current drug sensitivity screenings present several challenges including differences in cell growth rates, the inconsistent use of drug metrics, and...

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Detalles Bibliográficos
Autores principales: Calar, Kristin, Plesselova, Simona, Bhattacharya, Somshuvra, Jorgensen, Megan, de la Puente, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407241/
https://www.ncbi.nlm.nih.gov/pubmed/32610529
http://dx.doi.org/10.3390/cancers12071722